OPTIFAST Mini Program Don’t want to commit to a long program, but still want to reap the benefits of a program with a full formula component? OPTIFAST Mini could be what you are looking for. Participants in this 12-week program begin with a liquid diet, similar to the full OPTIFAST program, providing a jump start for weight loss. They will be medically monitored during this time. Participants then transition down to three OPTIFAST meal replacements a day plus a regular meal for a calorie controlled meal plan. Optifast Mini participants are provided the same lifestyle education as the Full program participants.