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We’re here to help you understand and manage amyloidosis — a serious cause of heart disease. The Sands-Constellation Heart Institute’s Amyloid Center offers comprehensive evaluation, diagnosis, and care for patients with suspected or confirmed cardiac amyloidosis. 

 

Why Amyloidosis Matters

Amyloidosis occurs when abnormal proteins – amyloids – build up in different tissues throughout the body. Amyloidosis can affect the nerves, heart, kidneys, gastrointestinal track, and skin. When this occurs in the heart, it makes the heart stiff and less effective at pumping blood. It is often underdiagnosed because its symptoms can resemble those of other heart conditions. Early recognition and treatment can improve quality and quantity of life.

 

Signs & Symptoms to Watch For

symbol breathe

Shortness of breath

symbol foot swelling

Swelling in the legs

symbol carpal tunnel

Carpal tunnel syndrome

symbol fatigue pillow

Unexplained fatigue

symbol spinal stenosis

Spinal stenosis

symbol hand tingling

Numbness or tingling

symbol weakness climbing steps

Difficulty walking

symbol blood pressure

Low blood pressure

symbol atrial fibrillation

Atrial fibrillation

symbol breathe

Shortness of breath

symbol foot swelling

Swelling in the legs

symbol carpal tunnel

Carpal tunnel syndrome

symbol fatigue pillow

Unexplained fatigue

symbol spinal stenosis

Spinal stenosis

symbol hand tingling

Numbness or tingling

symbol weakness climbing steps

Difficulty walking

symbol blood pressure

Low Blood Pressure

symbol atrial fibrillation

Atrial fibrillation

What to Expect

Our evaluation process is designed to be thorough yet comfortable for you. Your care team will:

  • Review your medical and family history
  • Assess symptoms and perform a physical exam
  • Order specialized heart imaging or tests as needed (such as echocardiogram, MRI, or bone scan)
  • Discuss findings and treatment options with you and your loved ones

Conditions We Treat

  • Wild-type transthyretin amyloidosis (wtATTR)
  • Hereditary transthyretin amyloidosis (hATTR)
  • Light-chain (AL) amyloidosis (in coordination with hematology)
  • Other forms of cardiac amyloidosis
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